It's the third of a generous five Saturdays in the month of November. What did we do to deserve such a bounty of days off? In the last week, we reported on hundreds of developments in science. Here is a more or less arbitrary sampling of them: Researchers reported on intra-regional brain dynamics linked to individual-specific characteristics; an AI model called AlphaProof delivers 100% correct answers to complex mathematical problems; and scientists found that a twice-weekly microdose of LSD over eight weeks reduces clinical depression scores without major side effects.