A skin-permeable polymer for non-invasive transdermal insulin delivery

www.nature.com

A skin-permeable polymer for non-invasive transdermal insulin delivery

www.nature.com

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NatureEnglish · 5 days ago

Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09729-x

The fast skin-permeable polyzwitterion poly[2-(N-oxide-N,N-dimethylamino)ethyl methacrylate] may enable non-invasive transdermal delivery of insulin, and potentially facilitate the use of other protein- and peptide-based therapeutics through transdermal delivery.

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