Rewiring an olfactory circuit by altering cell-surface combinatorial code

www.nature.com

Rewiring an olfactory circuit by altering cell-surface combinatorial code

www.nature.com

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NatureEnglish · 6 days ago

Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09769-3

In Drosophila, changing the expression of a small set of cell-surface proteins in just one type of olfactory neuron rewires its connections almost entirely to a new postsynaptic partner neuron type, altering the fly’s odour response and courtship behaviour.

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