Tumour-reactive heterotypic CD8 T cell clusters from clinical samples

www.nature.com

Tumour-reactive heterotypic CD8 T cell clusters from clinical samples

www.nature.com

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NatureEnglish · 4 days ago

Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09754-w

Tumour-reactive CD8+ T cells are enriched in functional clusters with tumour cells and/or antigen-presenting cells and can be isolated and expanded from clinical samples.

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Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

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