Modelling late gastrulation in stem cell-derived monkey embryo models

www.nature.com

Modelling late gastrulation in stem cell-derived monkey embryo models

www.nature.com

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NatureEnglish · 4 days ago

Nature, Published online: 03 December 2025; doi:10.1038/s41586-025-09831-0

An optimized 3D culture system enabled a stem cell-derived monkey blastoid to develop to day 25, recapitulating key events of primate late gastrula and demonstrating notable similarity to natural embryos.

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Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

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