More than half a million people, the vast majority being children under the age of 5, die annually due to malaria, with Sub-Saharan Africa as the most highly burdened region. Mosquitoes belonging to the genus Anopheles carry Plasmodium parasites and infect humans, occasionally causing severe symptoms. Control of the mosquito vector by means of insecticides has greatly contributed to malaria prevention so far; nevertheless, these successful efforts are seriously undermined by the rapid development and spread of insecticide resistance in wild Anopheles populations.