A direct role for a mitochondrial targeting sequence in signalling stress

www.nature.com

A direct role for a mitochondrial targeting sequence in signalling stress

www.nature.com

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NatureEnglish · 2 days ago

Nature, Published online: 10 December 2025; doi:10.1038/s41586-025-09834-x

Cells can sense mitochondrial damage through signalling via an unimported mitochondrial targeting sequence.

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Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

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