GlycoRNA complexed with heparan sulfate regulates VEGF-A signalling

www.nature.com

GlycoRNA complexed with heparan sulfate regulates VEGF-A signalling

www.nature.com

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NatureEnglish · 1 month ago

Nature, Published online: 28 January 2026; doi:10.1038/s41586-025-10052-8

Heparan sulfate proteoglycans facilitate the assembly of clusters of glycoRNAs and cell surface RNA-binding proteins, which negatively modulate VEGF-A signalling and angiogenesis.

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