PAF15–PCNA exhaustion governs the strand-specific control of DNA replication

www.nature.com

PAF15–PCNA exhaustion governs the strand-specific control of DNA replication

www.nature.com

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NatureEnglish · 1 month ago

Nature, Published online: 28 January 2026; doi:10.1038/s41586-025-10011-3

PCNA–PAF15 has a key role in determining replisome dynamics during genome replication and protecting against genome instability.

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