Cholinergic modulation of dopamine release drives effortful behaviour

www.nature.com

Cholinergic modulation of dopamine release drives effortful behaviour

www.nature.com

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NatureEnglish · 25 days ago

Nature, Published online: 28 January 2026; doi:10.1038/s41586-025-10046-6

In the nucleus accumbens, acetylcholine boosts dopamine release to promote effortful behaviour.

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