PtdIns(3,5)P₂ is an endogenous ligand of STING in innate immune signalling

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PtdIns(3,5)P₂ is an endogenous ligand of STING in innate immune signalling

www.nature.com

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NatureEnglish · 26 days ago

Nature, Published online: 04 February 2026; doi:10.1038/s41586-025-10084-0

Phosphatidylinositol 3,5-bisphosphate is a ligand of STING and, together with cGAMP, induces STING activation and innate immune responses.

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