Ancient co-option of LTR retrotransposons as yeast centromeres

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Ancient co-option of LTR retrotransposons as yeast centromeres

www.nature.com

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NatureEnglish · 10 days ago

Nature, Published online: 18 February 2026; doi:10.1038/s41586-025-10092-0

Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with retrotransposon-rich centromeres and that long-terminal-repeat retrotransposons are the genetic substrate.

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