Parkinson’s disease affects network of brain regions that controls whole-body action

www.nature.com

Parkinson’s disease affects network of brain regions that controls whole-body action

www.nature.com

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NatureEnglish · 1 month ago

Nature, Published online: 25 February 2026; doi:10.1038/d41586-026-00573-1

Precision brain imaging of individuals with Parkinson’s disease reveals that the affected circuit is best characterized as a previously described network of brain regions called the somato-cognitive action network. Abnormally high connectivity in this network is associated with Parkinson’s disease and is normalized by effective pharmacological treatment and various brain-stimulation therapies.

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