OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours

www.nature.com

OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours

www.nature.com

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NatureEnglish · 2 days ago

Nature, Published online: 25 February 2026; doi:10.1038/s41586-026-10149-8

The identification of ‘boosters’ that drive gene overexpression directly in a CAR construct provides a simple and scalable strategy for developing effective CAR-NK cell therapies for solid tumours.

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