Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma

www.nature.com

Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma

www.nature.com

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NatureEnglish · 12 days ago

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6

Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.

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