Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair

www.nature.com

Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair

www.nature.com

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NatureEnglish · 4 days ago

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10290-4

The transcription factor ATF4 is shown to regulate double-stranded DNA repair within vulnerable CUX2+ upper-layer 2/3 cortical neurons, enabling their survival during development.

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