Rare skeletal condition caused by enzyme’s failure to rescue a catalytic cycle

www.nature.com

Rare skeletal condition caused by enzyme’s failure to rescue a catalytic cycle

www.nature.com

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NatureEnglish · 2 days ago

Nature, Published online: 20 August 2025; doi:10.1038/d41586-025-02428-7

When enzymes require rescue strategies to complete progression through their reaction, but natural safety nets fail, disease states can ensue.

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