Thioester-mediated RNA aminoacylation and peptidyl-RNA synthesis in water

www.nature.com

Thioester-mediated RNA aminoacylation and peptidyl-RNA synthesis in water

www.nature.com

paywallMB to

NatureEnglish · 6 months ago

Nature, Published online: 27 August 2025; doi:10.1038/s41586-025-09388-y

Aminoacyl-thiols reacting selectively with RNA diols over amine nucleophiles and demonstration of chemically controlled formation of peptidyl-RNA in water at neutral pH suggest an important role for thiol cofactors before the evolution of enzymes.

From Nature via this RSS feed

You must log in or # to comment.

Chat

Nature

nature

You are not logged in. However you can subscribe from another Fediverse account, for example Lemmy or Mastodon. To do this, paste the following into the search field of your instance: !nature@ibbit.at

Community locked: only moderators can create posts. You can still comment on posts.

Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

Don’t post archive.is links or full text of articles, you will receive a temp ban.

Visibility: Public

This community can be federated to other instances and be posted/commented in by their users.

2 users / day
19 users / week
40 users / month
78 users / 6 months
1 local subscriber
30 subscribers
2.65K Posts
19 Comments
Modlog