Spatial joint profiling of DNA methylome and transcriptome in tissues

www.nature.com

Spatial joint profiling of DNA methylome and transcriptome in tissues

www.nature.com

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NatureEnglish · 3 days ago

Nature, Published online: 03 September 2025; doi:10.1038/s41586-025-09478-x

DNA-methylation and gene-expression profiling of tissue sections at near single-cell resolution can be used to create detailed spatial maps showing how methylation and transcription interact to shape cell identity and tissue development.

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