The formation and propagation of human Robertsonian chromosomes

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The formation and propagation of human Robertsonian chromosomes

www.nature.com

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NatureEnglish · 2 days ago

Nature, Published online: 24 September 2025; doi:10.1038/s41586-025-09540-8

Analysis of human Robertsonian chromosomes originating from 13, 14 and 21 reveal that they result from breaks at the SST1 macrosatellite DNA array and recombination between homologous sequences surrounding SST1.

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