Elaborate machinery for inserting proteins into the outer membrane of bacteria

www.nature.com

Elaborate machinery for inserting proteins into the outer membrane of bacteria

www.nature.com

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NatureEnglish · 1 day ago

Nature, Published online: 01 October 2025; doi:10.1038/d41586-025-03154-w

Bacteria insert proteins into their outer membrane using a highly conserved apparatus known as the β-barrel assembly machinery (BAM). A large group of bacteria with particularly complex outer-membrane proteins is now shown to have a BAM apparatus with a highly unusual composition.

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Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

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